Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504321 | 0.89 | PTPN1 (0.37) | PTPN1MAPTALDH1A1CHRM1CHRM3 | |
| SCHEMBL4495896 | 0.86 | MAPT (0.34) | MAPTALDH1A1CHRM1CHRM3MLNR | |
| SCHEMBL4509666 | 0.83 | PTPN1 (0.34) | PTPN1CHRM1CHRM3MLNRNR1I2 | |
| SCHEMBL4499078 | 0.82 | PTPN1 (0.38) | PTPN1MAPTALDH1A1CHRM1CHRM3 | |
| SCHEMBL14259012 | 0.81 | PTPN1 (0.37) | PTPN1MAPTALDH1A1CHRM1CHRM3 | |
| SCHEMBL4505513 | 0.76 | PTPN1 (0.34) | PTPN1CHRM1CHRM3MLNRNR1I2 | |
| SCHEMBL4504323 | 0.74 | BLM (0.36) | PTPN1MAPTCHRM1CHRM3MLNR | |
| SCHEMBL4504307 | 0.74 | BLM (0.36) | PTPN1MAPTCHRM1CHRM3MLNR | |
| SCHEMBL4504310 | 0.74 | BLM (0.36) | PTPN1MAPTCHRM1CHRM3MLNR | |
| SCHEMBL13292510 | 0.73 | PTPN1 (0.38) | PTPN1MAPTALDH1A1CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |