Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057435 | 1.00 | ESR1 (0.48) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL2057166 | 1.00 | ESR1 (0.48) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL2057436 | 1.00 | ESR1 (0.48) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL12935854 | 0.80 | ESR1 (0.55) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL15592583 | 0.75 | ESR1 (0.57) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL12901044 | 0.73 | ESR1 (0.43) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL4567101 | 0.72 | ESR1 (0.51) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL13019511 | 0.72 | ESR1 (0.51) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL13943802 | 0.72 | ESR1 (0.44) | ESR1ESR2GPR3MEN1KMT2A | |
| SCHEMBL12955756 | 0.71 | ESR1 (0.53) | ESR1ESR2GPR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| WO-2008027075-A2 | SULFHYDRYL-REACTIVE, WATER SOLUBLE DYES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-03-06 | — | — | WO | disclosed |