Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1402133 | 0.93 | ADORA2A (0.59) | ADORA2AADORA3 | |
| SCHEMBL1401975 | 0.92 | ADORA2A (0.59) | ADORA2AADORA3 | |
| SCHEMBL1401968 | 0.92 | ADORA2A (0.58) | ADORA2AADORA3 | |
| SCHEMBL1401988 | 0.92 | ADORA2A (0.59) | ADORA2AADORA3 | |
| SCHEMBL4125146 | 0.91 | ADORA2A (0.58) | ADORA2AADORA3 | |
| Trifluoroacetic Acid SCHEMBL4497991 | 0.91 | ADORA2A (0.68) | ADORA2AADORA3 | |
| SCHEMBL4224340 | 0.89 | ADORA2A (0.61) | ADORA2AADORA3 | |
| SCHEMBL4224344 | 0.88 | ADORA2A (0.63) | ADORA2AADORA3 | |
| SCHEMBL590746 | 0.87 | ADORA2A (0.58) | ADORA2AADORA3 | |
| SCHEMBL590745 | 0.85 | ADORA2A (0.58) | ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281127-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281127-A1 | Organic Compounds | CYP3A43, CYP3A4, CYP2C19 | ADORA2A 2387/4885ADORA3 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.