Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494240 | 0.92 | HDAC4 (0.39) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL4505852 | 0.84 | ERCC5 (0.37) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL4508104 | 0.81 | MEN1 (0.45) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL7201251 | 0.80 | HDAC4 (0.48) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL5164306 | 0.80 | HDAC4 (0.48) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL4504478 | 0.79 | MEN1 (0.52) | HDAC4MEN1KMT2APGRHSD17B1 | |
| SCHEMBL4496044 | 0.79 | MEN1 (0.49) | HDAC4MEN1KMT2APGRKDM4E | |
| SCHEMBL5163897 | 0.79 | HDAC4 (0.64) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL4510892 | 0.78 | KMT2A (0.63) | HDAC4MEN1KMT2APGRHIF1A | |
| SCHEMBL7614121 | 0.78 | HDAC4 (0.46) | HDAC4MEN1KMT2APGRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553849-B2 | Compounds | ACTIVE BIOTECH AB (SE) | 2009-06-30 | — | — | US | disclosed |
| EP-1776369-B1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| EP-1776369-A1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | Active Biotech AB (SE) | 2007-04-25 | — | — | EP | disclosed |
| US-20060004038-A1 | Novel compounds | ACTIVE BIOTECH AB (SE) | 2006-01-05 | — | — | US | disclosed |
| WO-2005123744-A1 | THIENOPYRIDONE CARBOXAMIDES AND THEIR MEDICAL USE | ACTIVE BIOTECH AB (SE) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004038-A1 | Novel compounds | REL, CLIC4, C5 | HDAC4 424/4885MEN1 509/4885KMT2A 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.