⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940168 | 0.79 | — | — | |
| SCHEMBL11180531 | 0.79 | — | — | |
| SCHEMBL68155 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL5415419 | 0.72 | — | — | |
| SCHEMBL871561 | 0.72 | — | — | |
| SCHEMBL1446441 | 0.72 | — | — | |
| SCHEMBL8571642 | 0.71 | — | — | |
| SCHEMBL11573021 | 0.69 | — | — | |
| SCHEMBL4613065 | 0.67 | — | — | |
| SCHEMBL8571666 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175141-B2 | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof | BIOFILM IP, LLC (US) | 2015-11-03 | — | — | US | disclosed |
| EP-2601245-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | Biofilm IP, LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| US-20120064022-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM, INC. | 2012-03-15 | — | — | US | disclosed |
| WO-2012018403-A1 | CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF | BIOFILM IP, LLC (US) | 2012-02-09 | — | — | WO | disclosed |
| US-7319129-B2 | Silsesquioxane derivative and process for producing the same | CHISSO CORPORATION (JP) | 2008-01-15 | — | — | US | disclosed |
| US-20060052623-A1 | Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance | CHISSO CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| US-4138349-A | FOR LUBRICATING SOFT METALS SUCH AS COPPER OR BRONZE | GENERAL ELECTRIC COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4071316-A | Silicone composition for analyzing blood samples | GENERAL ELECTRIC COMPANY (US) | 1978-01-31 | — | — | US | disclosed |