SCHEMBL449939

SCHEMBL449939

CCCCCCCCc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.54
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53
HIF1A Q16665 1/20 0.53
TST Q16762 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21634393 1.00 HTR2A (0.54) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL2493792 1.00 HTR2A (0.54) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL11204938 1.00 HTR2A (0.54) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL27480376 1.00 HTR2A (0.54) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL18317068 0.98 TRPV1 (0.53) HTR2AESR1ADRA2AADORA3TACR2
Diphenylamine SCHEMBL27639994 0.94 KCNH2 (0.59) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL2539187 0.92 TRPV1 (0.58) SLC6A2ALDH1A1LMNAHSD17B10PTGS1
SCHEMBL9330410 0.92 ESR1 (0.61) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL2391508 0.92 ESR1 (0.61) HTR2AESR1ADRA2AADORA3TACR2
SCHEMBL284616 0.92 ESR1 (0.61) HTR2AESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3410034-B1 REFRIGERATION DEVICE DAIKIN IND LTD (JP) 2022-11-23 EP claimed
US-11352532-B2 Refrigeration apparatus DAIKIN INDUSTRIES, LTD. (JP) 2022-06-07 US claimed
EP-3504307-B1 MARINE DIESEL CYLINDER LUBRICANT OIL COMPOSITIONS CHEVRON ORONITE TECH BV (NL) 2022-05-11 EP claimed
CN-114381316-A Magnetic molybdenum-titanium lubricating oil and preparation method thereof 邦仕顿润滑科技股份有限公司 2022-04-22 CN claimed
CN-111879022-B Refrigerating device 大金工业株式会社 2022-04-05 CN claimed
CN-114085697-A Poly-alpha-olefin lubricating oil and preparation method thereof 邦仕顿润滑科技股份有限公司 2022-02-25 CN claimed
CN-112608402-B Styrene block copolymer and preparation method thereof 北京化工大学 2022-02-11 CN claimed
CN-113930279-A Biodegradable plant-based anti-wear lubricating oil and preparation method thereof 邦仕顿润滑科技股份有限公司 2022-01-14 CN claimed
US-11085677-B2 Refrigerant recovery device and refrigerant recovery method DAIKIN INDUSTRIES, LTD. (JP) 2021-08-10 US claimed
CN-112608402-A Styrene block copolymer and preparation method thereof 北京化工大学 2021-04-06 CN claimed
EP-1963467-A1 A COMPOSITION OF HYDRAULIC FLUID AND PROCESS FOR THE PREPARETION THEREOF Council of Scientific & Industrial Research (IN) 2008-09-03 EP claimed
WO-2007089645-A2 BIODIESEL FUEL ADDITIVE ORYXE ENERGY INTERNATIONAL, INC. (US) 2007-08-09 WO claimed
WO-2007066348-A1 A COMPOSITION OF LUBRICATING OIL FOR TWO STROKE GASOLINE ENGINE AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-06-14 WO claimed
WO-2007066349-A1 A COMPOSITION OF HYDRAULIC FLUID AND PROCESS FOR THE PREPARETION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-06-14 WO claimed
US-20070135318-A1 Composition of lubricating oil for two stroke gasoline engine and process for the preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2007-06-14 US claimed
US-20070060484-A1 Composition of insulating fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
US-20070060486-A1 Composition of hydraulic fluid and process for the preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-03-15 US claimed
US-20060201056-A1 Biodiesel fuel additive ORYXE ENERGY INTERNATIONAL, INC. (US) 2006-09-14 US claimed
EP-0799289-B1 SYNTHETIC LUBRICANT ANTIOXIDANT FROM MONOSUBSTITUTED DIPHENYLAMINES NOVEON IP HOLDINGS CORP (US) 2002-07-31 EP claimed
US-4116874-A AROMATIC AMINE, ALKYLPHENOL, TRIESTER OF DITHIOPHOSPHORIC ACID NIPPON OIL CO., LTD. (JP) 1978-09-26 US claimed