Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13817516 | 0.95 | FFAR1 (0.37) | FFAR1SMN1; SMN2TLR8THRBTHRA | |
| SCHEMBL4486868 | 0.91 | FFAR1 (0.42) | FFAR1THRBTHRANPC1RAB9A | |
| SCHEMBL13817517 | 0.87 | FFAR1 (0.41) | FFAR1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL4506759 | 0.85 | FFAR1 (0.43) | FFAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4491357 | 0.83 | FFAR1 (0.40) | FFAR1SMN1; SMN2THRBTHRALMNA | |
| SCHEMBL4492426 | 0.83 | FFAR1 (0.39) | FFAR1NPC1RAB9AALDH1A1MRGPRX4 | |
| SCHEMBL4487410 | 0.82 | CTSA (0.42) | FFAR1NPC1RAB9A | |
| SCHEMBL13817470 | 0.81 | IDO1 (0.42) | FFAR1MEN1KMT2ACNR2 | |
| SCHEMBL4496418 | 0.81 | CTSA (0.42) | FFAR1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL4484469 | 0.81 | CNR2 (0.35) | FFAR1SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | ATP CAPITAL LP | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094739-A1 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CYP51A1, DDT, CYP21A2 | FFAR1 304/4885SMN1; SMN2 1516/4885TLR8 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.