SCHEMBL450001

SCHEMBL450001

[SiH2]O[SiH2]O[SiH2]O[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445969 0.97
SCHEMBL450516 0.97
SCHEMBL448029 0.97
SCHEMBL448449 0.97
SCHEMBL449026 0.97
SCHEMBL448318 0.97
SCHEMBL447840 0.97
SCHEMBL445532 0.97
SCHEMBL446277 0.97
SCHEMBL3065010 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601245-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF Biofilm IP, LLC (US) 2013-06-12 EP claimed
US-20120064022-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM, INC. 2012-03-15 US claimed
WO-2012018403-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM IP, LLC (US) 2012-02-09 WO claimed
US-4826936-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORP. (US) 1989-05-02 US claimed
US-4424328-A POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-01-03 US claimed
US-9175141-B2 Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof BIOFILM IP, LLC (US) 2015-11-03 US disclosed
EP-2601245-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF Biofilm IP, LLC (US) 2013-06-12 EP disclosed
US-20120064022-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM, INC. 2012-03-15 US disclosed
WO-2012018403-A1 CYCLOSILOXANE-SUBSTITUTED POLYSILOXANE COMPOUNDS, COMPOSITIONS CONTAINING THE COMPOUNDS AND METHODS OF USE THEREOF BIOFILM IP, LLC (US) 2012-02-09 WO disclosed
US-4826936-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORP. (US) 1989-05-02 US disclosed
US-4649208-A COMPLEX OF PLATINUM AND AN OLEFIN WITH AN AMINO COMPOUND AS CATALYSTS TOSHIBA SILICONE CO., LTD. (JP) 1987-03-10 US disclosed
US-4604479-A Silicone-containing contact lens material and contact lenses made thereof POLYMER TECHNOLOGY CORPORATION (US) 1986-08-05 US disclosed
US-4424328-A POLYMERS OF UNSATURATED MULTIFUNCTIONAL POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-01-03 US disclosed