Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 16/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 16/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 16/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 16/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.42 |
| ▸ | DRD2 | P14416 | 12/20 | 0.42 |
| ▸ | DRD3 | P35462 | 12/20 | 0.42 |
| ▸ | DRD4 | P21917 | 11/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096528 | 0.91 | CHRM1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4096526 | 0.91 | CHRM1 (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4096268 | 0.89 | DRD3 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4096266 | 0.89 | DRD3 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4097824 | 0.78 | CHRM1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4097825 | 0.78 | CHRM1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4096001 | 0.77 | CHRM1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4095999 | 0.77 | CHRM1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6437869 | 0.77 | CHRM1 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4090302 | 0.76 | CHRM1 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576100-B2 | Muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2009-08-18 | — | — | US | claimed |