Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.71 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | CLK1 | P49759 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.69 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15377151 | 0.90 | DYRK1A (0.68) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10872327 | 0.85 | DYRK1A (0.62) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL3142565 | 0.84 | DYRK1A (0.63) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL31060991 | 0.83 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL16992945 | 0.83 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL130572 | 0.83 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL10170616 | 0.83 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL2175580 | 0.83 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL856499 | 0.82 | DYRK1A (1.00) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL8247153 | 0.82 | DYRK1A (0.71) | DYRK1ANPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258857-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | US | claimed |
| US-8203001-B2 | Chemical compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20090258857-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258857-A1 | CHEMICAL COMPOUNDS | CCNA1, CCNT1, MKI67 | DYRK1A 3410/4885NPC1 93/4885RAB9A 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.