⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228656 | 1.00 | — | — | |
| SCHEMBL5553044 | 1.00 | — | — | |
| SCHEMBL6618773 | 0.93 | — | — | |
| SCHEMBL16796790 | 0.81 | — | — | |
| SCHEMBL2174728 | 0.81 | — | — | |
| SCHEMBL2174724 | 0.81 | — | — | |
| SCHEMBL15490985 | 0.80 | — | — | |
| SCHEMBL1935783 | 0.79 | — | — | |
| SCHEMBL1935786 | 0.79 | — | — | |
| SCHEMBL15220962 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018133-A1 | Novel Adamantane Derivatives | FORD RHONAN | 2009-01-15 | — | — | US | disclosed |
| US-7227038-B2 | Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them | ASTRAZENECA AB (SE) | 2007-06-05 | — | — | US | disclosed |
| US-20060160904-A1 | Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them | ASTRAZENECA AB (SE) | 2006-07-20 | — | — | US | disclosed |
| EP-1599432-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | AstraZeneca AB (SE) | 2005-11-30 | — | — | EP | disclosed |
| US-20050090524-A1 | Novel adamantane derivatives | ASTRAZENECA AB (SE) | 2005-04-28 | — | — | US | disclosed |
| WO-2004074224-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |