Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 19/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469867 | 0.94 | PRKCQ (0.72) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL5470712 | 0.85 | PRKCQ (1.00) | PRKCQPRKCDPRKCHPRKCEGAK | |
| SCHEMBL4199624 | 0.84 | PRKCQ (0.74) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL5469863 | 0.82 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCEEGFR | |
| SCHEMBL5470678 | 0.82 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCEEGFR | |
| SCHEMBL4493784 | 0.80 | PRKCQ (0.66) | PRKCQPRKCDPRKCHPRKCEEGFR | |
| SCHEMBL5481843 | 0.79 | PRKCQ (1.00) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL5473112 | 0.79 | PRKCQ (1.00) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL4190457 | 0.79 | PRKCQ (1.00) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL4194582 | 0.78 | PRKCQ (1.00) | PRKCQPRKCDPRKCHPRKCEEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027093-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2007146323-A2 | SUBSTITUTED CYANOPYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2007-12-21 | — | — | WO | claimed |