⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519118 | 0.84 | — | — | |
| SCHEMBL61422 | 0.80 | — | — | |
| SCHEMBL518639 | 0.78 | — | — | |
| SCHEMBL9205 | 0.75 | — | — | |
| SCHEMBL4608960 | 0.73 | — | — | |
| SCHEMBL23752 | 0.73 | — | — | |
| SCHEMBL17784330 | 0.73 | — | — | |
| SCHEMBL4608962 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL29240889 | 0.72 | — | — | |
| SCHEMBL8805 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | Tonix Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | claimed |
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| WO-2023177233-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | (주)아름테라퓨틱스 | 2023-09-21 | — | — | WO | disclosed |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | disclosed |
| EP-3860980-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2021-08-11 | — | — | EP | disclosed |
| CN-105611930-B | Spiro quinoxaline derivatives as non-apoptotic regulated cell death inhibitors | 亥姆霍兹慕尼黑中心-德国环境与健康研究中心（股份有限公司） | 2021-03-02 | — | — | CN | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| WO-2020072695-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| US-20200108075-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2020-04-09 | — | — | US | disclosed |
| WO-2020027304-A1 | NOVEL CAROTENOID-RELATED DERIVATIVES, AND SALTS, ESTERS, OR AMIDES THEREOF | アスタファーマシューティカルズ株式会社 | 2020-02-06 | — | — | WO | disclosed |
| WO-2005118587-A1 | INDOLE DERIVATIVE AND USE FOR TREATMENT OF CANCER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-15 | — | — | WO | disclosed |
| US-20050176966-A1 | Process for the preparation of pyrimidine derivative, intermediate therefor and process for the preparation thereof | AJINOMOTO CO., INC. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20050130251-A1 | Reagent for determination of hydrogen peroxide | KYOWA MEDEX CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1529778-A1 | Production method of pyrimidine derivative, intermediate therefor | Ajinomoto Co., Inc. (JP) | 2005-05-11 | — | — | EP | disclosed |
| EP-1424554-A1 | REAGENT FOR DETERMINING HYDROGEN PEROXIDE | KYOWA MEDEX CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |