SCHEMBL450560

SCHEMBL450560

CC[CH]OC(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452702 0.80
SCHEMBL7965859 0.77
SCHEMBL7965893 0.77
SCHEMBL450031 0.77 CA1 (0.39)
SCHEMBL14775406 0.75
SCHEMBL14775405 0.75
SCHEMBL8696684 0.75 MAPT (0.32)
SCHEMBL451856 0.75 TSHR (0.45)
SCHEMBL452560 0.75 ZDHHC7 (0.40)
SCHEMBL8694249 0.73 HDAC6 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240131180-A1 DRUG ANTIBODY CONJUGATES PHARMA MAR, S.A. (ES) 2024-04-25 US disclosed
EP-4025253-B1 DRUG ANTIBODY CONJUGATES PHARMA MAR SA (ES) 2024-03-20 EP disclosed
CN-114615999-B Drug antibody conjugates 法马马有限公司 2024-03-08 CN disclosed
US-20230218774-A1 DRUG ANTIBODY CONJUGATES PHARMA MAR, S.A. (ES) 2023-07-13 US disclosed
EP-4138923-A1 DRUG ANTIBODY CONJUGATES Pharma Mar, S.A. (ES) 2023-03-01 EP disclosed
US-20230012681-A1 ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES PHARMA MAR, S.A. (ES) 2023-01-19 US disclosed
EP-3870234-B1 ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES PHARMA MAR SA (ES) 2022-12-21 EP disclosed
EP-4025253-A1 DRUG ANTIBODY CONJUGATES Pharma Mar S.A. (ES) 2022-07-13 EP disclosed
CN-114615999-A Drug antibody conjugates 法马马有限公司 2022-06-10 CN disclosed
US-20220168436-A1 ANTIBODY DRUG CONJUGATES PHARMA MAR SA (ES) 2022-06-02 US disclosed
US-4323567-A BACTERICIDES NARISADA MASAYUKI 1982-04-06 US disclosed
US-4271295-A HALOGENATION STEP SHIONOGI & CO., LTD. (JP) 1981-06-02 US disclosed
US-4271296-A CEPHALOSPORINS AND DERIVATIVES SHIONOGI & CO., LTD. (JP) 1981-06-02 US disclosed
US-4233216-A INTERMEDIATES FOR OXADETHIACEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1980-11-11 US disclosed
US-4220766-A FROM PENICILLINS SHIONOGI & CO., LTD. (JP) 1980-09-02 US disclosed
US-4203982-A Arylmalonamidomethoxycephalosporins SHIONOGI & CO., LTD. (JP) 1980-05-20 US disclosed
US-4201782-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1980-05-06 US disclosed
US-4183855-A INTERMEDIATES FOR PREPARATION OF THE BACTERICIDE, 1-OXADETHIA-CEPHALOSPORIN SHIONOGI & CO., LTD. (JP) 1980-01-15 US disclosed
US-4180571-A Arylmalonamido-1-oxadethiacephalosporins SHIONOGI & CO., LTD. (JP) 1979-12-25 US disclosed
US-4138486-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1979-02-06 US disclosed