Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 16/20 | 0.51 |
| ▸ | MEN1 | O00255 | 13/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | THRB | P10828 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057334 | 1.00 | HTT (0.52) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL2057338 | 1.00 | HTT (0.52) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL2057342 | 1.00 | HTT (0.52) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL13292510 | 0.81 | PTPN1 (0.38) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL2057099 | 0.79 | MEN1 (0.40) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL2057106 | 0.79 | MEN1 (0.40) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL23515503 | 0.76 | MAPT (0.54) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL13713099 | 0.76 | ESR1 (0.34) | HTTMAPTMEN1KMT2APOLB | |
| SCHEMBL9637127 | 0.75 | MAPT (0.77) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL9637124 | 0.75 | MAPT (0.77) | HTTLMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |