SCHEMBL451155

SCHEMBL451155

COC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
RECQL P46063 1/20 0.34
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30728090 0.97 GAA (0.39) GAARECQLATML3MBTL1MEN1
SCHEMBL8520745 0.97 GAA (0.39) GAARECQLATML3MBTL1MEN1
Acetic Acid SCHEMBL987785 0.87 GAA (0.49) GAAATML3MBTL1MEN1PKM
SCHEMBL11051607 0.80 GAA (0.41) GAARECQLL3MBTL1MEN1PKM
SCHEMBL15299565 0.79 GAA (0.38) GAARECQLATML3MBTL1
SCHEMBL19035783 0.79
SCHEMBL6663050 0.78 GAA (0.40) GAARECQL
SCHEMBL20261597 0.77
SCHEMBL4258075 0.76 GAA (0.43) GAARECQLATML3MBTL1MEN1
SCHEMBL5501687 0.76 GAA (0.39) GAARECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492221-B2 Process for preparing (3α,5α)-3-hydroxy-3-methyl-pregnan-20-one (Ganaxolone) INDUSTRIALE CHIMICA S.R.L. (IT) 2025-12-09 US claimed
US-12183932-B2 Electrochemical flow devices and methods of making the same GEORGIA TECH RESEARCH CORPORATION (US) 2024-12-31 US claimed
US-20240145730-A1 ELECTROCHEMICAL FLOW DEVICES AND METHODS OF MAKING THE SAME GEORGIA TECH RESEARCH CORPORATION 2024-05-02 US claimed
EP-4038113-B1 DECARBOXYLATION OF N-OXYPHTHALIMIDE-BASED POLYMERS KARLSRUHER INSTITUT FUER TECH KIT (DE) 2023-11-01 EP claimed
US-11767488-B2 Lubricant composition and rolling bearing having same sealed therein NSK LTD. (JP) 2023-09-26 US claimed
EP-3694842-B1 PROCESS FOR PREPARING 2,5-FURANDICARBOXYLIC ACID SYNPHABASE AG (CH) 2023-01-25 EP claimed
CN-115094543-A Inorganic fiber, preparation method and semi-aromatic nylon composition prepared from inorganic fiber 天津斯坦利新型材料有限公司 2022-09-23 CN claimed
EP-4038113-A1 DECARBOXYLATION OF N-OXYPHTHALIMIDE-BASED POLYMERS Karlsruher Institut Für Technologie (KIT) (DE) 2022-08-10 EP claimed
CN-114835549-A Anti-freezing water-soluble styrene polymerization inhibitor and preparation method thereof 广东耀辉化工有限公司 2022-08-02 CN claimed
WO-2017205515-A1 PROCEDURE FOR THE PREPARATION OF 4-PHENYL BUTYRATE AND USES THEREOF HORIZON THERAPEUTICS, LLC (US) 2017-11-30 WO claimed
US-5859098-A A LIGHT STABILIZER BENZOTRIAZOLE COMPOUND; AN ALIPHATIC FATTY ACID ESTER OBTAINED FROM A FATTY ACID AND A POLYALKYLENE GLYCOL; A HINDERED AMINE WHICH IS A PIPERIDINE DERIVATIVE POLYPLASTICS CO., LTD. (JP) 1999-01-12 US claimed
EP-0722946-B1 Process for the separation of 3-formyl-cephem derivatives HOFFMANN LA ROCHE (CH) 1998-08-19 EP claimed
EP-0523709-A1 Polyurethane composition KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-01-20 EP claimed
US-5142001-A Neutralization of a polyurethane containing hydrophilic acidic group with piperidine compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-08-25 US claimed
EP-0151042-B1 POLYACETAL RESIN COMPOSITION AND MOULDED PRODUCTS THEREOF POLYPLASTICS CO. LTD. (JP) 1988-08-17 EP claimed
US-4730015-A BENZOTRIAZOLE AND PIPERIDINE STABILIZER POLYPLASTICS CO., LTD. (JP) 1988-03-08 US claimed
US-6384179-B1 None US disclosed
EP-4737524-A1 INKJET INK, SOLDER RESIST, PRINTED WIRING BOARD, METHOD FOR FORMING COATING FILM, AND DEVICE FOR FORMING COATING FILM Konica Minolta, Inc. (JP) 2026-05-06 EP disclosed
US-4038218-A SPRAY DRYING KAO SOAP CO., LTD. (JA) 1977-07-26 US disclosed
US-4015990-A TOCOPHEROL DERIVATIVE AS STABILIZER MITSUBISHI PAPER MILLS, LTD. (JA) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492221-B2 Process for preparing (3α,5α)-3-hydroxy-3-methyl-pregnan-20-one (Ganaxolone) CYP17A1, CYP21A2, CYP4A11 GAA 3693/4885RECQL 2947/4885ATM 4312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.