Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.80 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL990887 | 0.99 | GRM5 (0.79) | GRM5HCAR3RECQLNAMPTALDH1A1 | |
| SCHEMBL27723141 | 0.90 | GRM5 (0.82) | GRM5RECQLKDM4ERAB9A | |
| SCHEMBL990086 | 0.89 | GRM5 (1.00) | GRM5RECQL | |
| SCHEMBL990084 | 0.89 | GRM5 (1.00) | GRM5RECQL | |
| SCHEMBL990182 | 0.89 | GRM5 (1.00) | GRM5RECQL | |
| Hydrochloric Acid SCHEMBL990917 | 0.87 | GRM5 (0.77) | GRM5ALDH1A1KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL990868 | 0.86 | GRM5 (0.76) | GRM5ALDH1A1 | |
| SCHEMBL990132 | 0.86 | GRM5 (0.76) | GRM5 | |
| SCHEMBL989586 | 0.86 | GRM5 (0.76) | GRM5 | |
| SCHEMBL989454 | 0.86 | GRM5 (0.76) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NOVARTIS AG (CH) | 2009-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005363-A1 | Organic Compounds | NNT, NAPRT, CHRNA5 | GRM5 680/4885HCAR3 184/4885RECQL 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.