Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094939 | 1.00 | MEN1 (0.47) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL12340683 | 0.89 | MEN1 (0.45) | MEN1KMT2AHDAC3NCOR2LMNA | |
| SCHEMBL6864687 | 0.89 | MEN1 (0.45) | MEN1KMT2AHDAC3NCOR2LMNA | |
| SCHEMBL12094878 | 0.85 | MEN1 (0.45) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL12094867 | 0.85 | MEN1 (0.45) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL12094868 | 0.76 | MEN1 (0.46) | MEN1KMT2AHDAC3NCOR2LMNA | |
| SCHEMBL12095114 | 0.76 | MEN1 (0.46) | MEN1KMT2AHDAC3NCOR2LMNA | |
| SCHEMBL12317390 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1HDAC6 | |
| SCHEMBL3233893 | 0.73 | HDAC3 (0.62) | MEN1KMT2AHDAC3NCOR2HDAC1 | |
| SCHEMBL3238191 | 0.73 | HDAC3 (0.62) | MEN1KMT2AHDAC3NCOR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | claimed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | claimed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | HDAC1, HDAC5, HDAC11 | MEN1 3883/4885KMT2A 265/4885HDAC3 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.