Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 13/20 | 0.49 |
| ▸ | CTSD | P07339 | 12/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519487 | 0.96 | BACE1 (0.53) | BACE1BACE2CTSD | |
| SCHEMBL4524954 | 0.91 | BACE1 (0.58) | BACE1BACE2CTSD | |
| Acetic Acid SCHEMBL4522917 | 0.89 | BACE1 (0.64) | BACE1BACE2CTSD | |
| SCHEMBL4520928 | 0.89 | BACE1 (0.53) | BACE1BACE2CTSD | |
| SCHEMBL4516312 | 0.85 | BACE1 (0.68) | BACE1BACE2CTSD | |
| SCHEMBL4517723 | 0.85 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL4524456 | 0.84 | BACE1 (0.57) | BACE1BACE2CTSD | |
| Acetic Acid SCHEMBL4534634 | 0.84 | BACE1 (0.56) | BACE1BACE2CTSD | |
| SCHEMBL4530743 | 0.83 | BACE1 (0.55) | BACE1BACE2CTSD | |
| SCHEMBL4516099 | 0.82 | BACE1 (0.52) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033236-A1 | SINGLE-ION CONDUCTING MATERIAL | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2024-02-15 | — | — | WO | claimed |
| EP-1940774-A1 | NEW SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS | Schwarz Pharma Ltd. (IE) | 2008-07-09 | — | — | EP | claimed |
| WO-2007137799-A1 | NEW SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS | SCHWARZ PHARMA LTD. (IE) | 2007-12-06 | — | — | WO | claimed |
| WO-2024033236-A1 | SINGLE-ION CONDUCTING MATERIAL | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2024-02-15 | — | — | WO | disclosed |
| WO-2023187138-A1 | BATTERY | SUMITOMO CHEMICAL CO., LTD (JP) | 2023-10-05 | — | — | WO | disclosed |
| CN-114008010-A | Isolation of bisphenol A by depolymerization of poly (carbonate) | 高新特殊工程塑料全球技术有限公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3898571-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | Shell Internationale Research Maatschappij B.V. (NL) | 2021-10-27 | — | — | EP | disclosed |
| WO-2021110627-A1 | PROCESS FOR REMOVING AN ETHER ALKANOL IMPURITY FROM AN ORGANIC CARBONATE STREAM | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021063853-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2021-04-08 | — | — | WO | disclosed |
| WO-2020126989-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2020-06-25 | — | — | WO | disclosed |
| US-20090233930-A9 | Novel 2-Amino-Imidazole-4-One Compounds and Their Use in the Manufacture of a Medicament to Be Used in the Treatment of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration and Dementia | ASTRAZENECA AB (SE) | 2009-09-17 | — | — | US | disclosed |
| EP-1979324-A2 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER'S DISEASE, NEURODEGENERATION AND DEMENTIA | Astra Zeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| EP-1940774-A1 | NEW SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS | Schwarz Pharma Ltd. (IE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007140965-A1 | ACCELERATED SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS | SCHWARZ PHARMA LTD. (IE) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007137799-A1 | NEW SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS | SCHWARZ PHARMA LTD. (IE) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007058602-A2 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA. | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |
| EP-0611214-A2 | Acidic composition and process of using same | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0103400-B1 | PROCESS FOR MAKING CARBOHYDRAZIDE | OLIN CORPORATION (US) | 1986-05-14 | — | — | EP | disclosed |
| US-4496761-A | Process for making carbohydrazide | OLIN CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0103400-A1 | Process for making carbohydrazide | OLIN CORPORATION (US) | 1984-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233930-A9 | Novel 2-Amino-Imidazole-4-One Compounds and Their Use in the Manufacture of a Medicament to Be Used in the Treatment of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration and Dementia | PSEN2, MAPT, PSEN1 | BACE1 14/4885BACE2 30/4885CTSD 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.