Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518575 | 1.00 | CNR2 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL4518297 | 0.93 | CNR2 (0.58) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3880504 | 0.91 | CNR2 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL4524342 | 0.91 | CNR2 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3880317 | 0.89 | CNR2 (0.55) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3882843 | 0.88 | CNR2 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL4528290 | 0.88 | CNR2 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3993825 | 0.87 | TP53 (0.59) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3880555 | 0.87 | S1PR1 (0.53) | CNR2TP53MAOAMAOBMAPT | |
| SCHEMBL3882994 | 0.87 | S1PR1 (0.53) | CNR2TP53MAOAMAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | NOVARTIS AG (CH) | 2009-12-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | CYP1A2, CYP4B1, CYP1B1 | CNR2 538/4885TP53 487/4885MAOA 1782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.