⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4472714 | 0.83 | — | — | |
| SCHEMBL3990531 | 0.76 | FFAR1 (0.31) | — | |
| SCHEMBL12340539 | 0.75 | MAPT (0.33) | — | |
| SCHEMBL3987748 | 0.74 | — | — | |
| SCHEMBL5880945 | 0.74 | ACACB (0.35) | — | |
| SCHEMBL1581458 | 0.73 | — | — | |
| SCHEMBL1581322 | 0.73 | — | — | |
| SCHEMBL3988830 | 0.72 | — | — | |
| SCHEMBL3987883 | 0.72 | — | — | |
| SCHEMBL1581635 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268835-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090281122-A1 | Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, and Compositions and Treatments Using the Same | PFIZER INC | 2009-11-12 | — | — | US | disclosed |