SCHEMBL45169

SCHEMBL45169

CCCCc1c(C(=O)O)cc(O)c(O)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.46
PPARA Q07869 1/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43
BCL2 P10415 1/20 0.43
MCL1 Q07820 1/20 0.43
LDHA P00338 1/20 0.43
LDHB P07195 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27729778 0.95 KAT8 (0.53) KAT8PPARAHCAR3HCAR2
SCHEMBL51647 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL9061592 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL221376 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL9061472 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL5709508 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL216726 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL719922 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL5160516 0.93 KAT8 (0.55) KAT8PPARAMCL1
SCHEMBL9061041 0.93 KAT8 (0.55) KAT8PPARAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850255-A1 THERMOPLASTIC VULCANIZATE COMPOSITIONS THEIR PREPARATION AND USE IN FLEXIBLE TUBULAR PIPES ExxonMobil Chemical Patents Inc. (US) 2021-07-21 EP claimed
WO-2020055709-A1 THERMOPLASTIC VULCANIZATE COMPOSITIONS THEIR PREPARATION AND USE IN FLEXIBLE TUBULAR PIPES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-03-19 WO claimed
US-6326426-B1 POLYOLEFIN ADVANCED ELASTOMER SYSTEMS, L.P. 2001-12-04 US claimed
US-5397832-A Ester plasticizers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1995-03-14 US claimed
US-5290886-A Blends of olefin homo or copolymers with olefin rubbers and plasticizers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1994-03-01 US claimed
JP-10259108-A None JP disclosed
US-11950596-B2 Methods of protecting seeds from oxidants and microorganisms THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-04-09 US disclosed
US-20230295401-A1 REINFORCEMENT AND FILLER MATERIALS AND COMPOSITES THEREOF UNIVERSITY OF WYOMING 2023-09-21 US disclosed
WO-2023177843-A1 REINFORCEMENT AND FILLER MATERIALS AND COMPOSITES THEREOF UNIVERSITY OF WYOMING (US) 2023-09-21 WO disclosed
US-20230193010-A1 Pipe Including a Polymethylpentene Thermoplastic Polymer CELANESE INT CORP (US) 2023-06-22 US disclosed
US-20230133171-A1 Thermoplastic Elastomer Compositions, Their Preparation and Use in Fiber-Reinforced Spoolable Pipes CELANESE INT CORP (US) 2023-05-04 US disclosed
EP-4146735-A1 PIPE INCLUDING A POLYMETHYLPENTENE THERMOPLASTIC POLYMER Celanese International Corporation (US) 2023-03-15 EP disclosed
WO-1998039385-A1 ELASTOMER COMPOSITIONS HAVING IMPROVED ABRASION RESISTANCE, COEFFICIENT OF FRICTION AND HOT GREEN STRENGTH DUPONT DOW ELASTOMERS L.L.C. (US) 1998-09-11 WO disclosed
EP-0621308-B1 Thermoplastic elastomers having improved low temperature properties ADVANCED ELASTOMER SYSTEMS (US) 1997-06-25 EP disclosed
EP-0768896-A2 LOW-DOSE STEROID TABLETS CONTAINING GALLIC ACID ESTERS AS ANTIOXIDANT AGENT, PROCESS FOR THE MANUFACTURE OF SAID TABLETS, AND USES OF SAID TABLETS SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-23 EP disclosed
WO-1996001128-A2 LOW-DOSE STEROID TABLETS CONTAINING GALLIC ACID ESTERS AS ANTIOXIDANT AGENT, PROCESS FOR THE MANUFACTURE OF SAID TABLETS, AND USES OF SAID TABLETS SCHERING AKTIENGESELLSCHAFT (DE) 1996-01-18 WO disclosed
US-5397832-A Ester plasticizers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1995-03-14 US disclosed
EP-0621308-A2 Thermoplastic elastomers having improved low temperature properties Advanced Elastomer Systems, L.P. (US) 1994-10-26 EP disclosed
US-5290886-A Blends of olefin homo or copolymers with olefin rubbers and plasticizers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1994-03-01 US disclosed
US-4372582-A 2,2'-METHYLENEBIS(4-METHYL-6-T-BUTYL PHENOL) AS A STABILIZING AGENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-02-08 US disclosed