Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 5/20 | 0.34 |
| ▸ | FPR1 | P21462 | 3/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | CALML3 | P27482 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451890 | 1.00 | KLKB1 (0.36) | KLKB1CYP11B1CYP11B2TAAR1ALOX5AP | |
| SCHEMBL447278 | 0.97 | KLKB1 (0.35) | KLKB1CYP11B1CYP11B2TAAR1ALOX5AP | |
| SCHEMBL447279 | 0.97 | KLKB1 (0.35) | KLKB1CYP11B1CYP11B2TAAR1ALOX5AP | |
| SCHEMBL1316667 | 0.84 | KLKB1 (0.36) | KLKB1CYP11B1CYP11B2TAAR1ALOX5AP | |
| SCHEMBL452407 | 0.84 | TAAR1 (0.36) | TAAR1BACE1HTR2AHTR2CHTR2B | |
| SCHEMBL452406 | 0.84 | TAAR1 (0.36) | TAAR1BACE1HTR2AHTR2CHTR2B | |
| SCHEMBL449376 | 0.81 | TAAR1 (0.34) | TAAR1BACE1HTR2AHTR2C | |
| SCHEMBL449377 | 0.81 | TAAR1 (0.34) | TAAR1BACE1HTR2AHTR2C | |
| SCHEMBL13366541 | 0.79 | GRM2 (0.33) | KLKB1CALML3CTSDBACE1MME | |
| SCHEMBL13220505 | 0.78 | ALOX5AP (0.41) | KLKB1ALOX5APFEN1CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2429979-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065066-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| WO-2010133232-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065066-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | KLKB1 4854/4885CYP11B1 745/4885CYP11B2 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.