SCHEMBL452053

SCHEMBL452053

[SiH3]N=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10834494 0.95
SCHEMBL244183 0.67
SCHEMBL28777937 0.59
Methylisothiocyanate SCHEMBL3152 0.56
SCHEMBL14164129 0.56
SCHEMBL344363 0.56
SCHEMBL6653692 0.56
SCHEMBL9617070 0.56
SCHEMBL8008548 0.56
SCHEMBL1534324 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570855-B2 Non-sag composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2026-03-10 US claimed
US-12202943-B2 Electrostatically dissipative room temperature vulcanizable silicone MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2025-01-21 US claimed
US-20220098370-A1 ELECTROSTATICALLY DISSIPATIVE ROOM TEMPERATURE VULCANIZABLE SILICONE MOMENTIVE PERFORMANCE MATERIALS INC. 2022-03-31 US claimed
EP-3891222-A1 ELECTROSTATICALLY DISSIPATIVE ROOM TEMPERATURE VULCANIZABLE SILICONE Momentive Performance Materials Inc. (US) 2021-10-13 EP claimed
CN-113260677-A Electrostatic dissipative room temperature vulcanizable silicones 迈图高新材料公司 2021-08-13 CN claimed
WO-2020260560-A1 PHOTO-STERILIZABLE MEDICAL DEVICE UNIVERSIDAD COMPLUTENSE DE MADRID (ES) 2020-12-30 WO claimed
WO-2020117719-A1 ELECTROSTATICALLY DISSIPATIVE ROOM TEMPERATURE VULCANIZABLE SILICONE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-06-11 WO claimed
EP-3555047-A1 T-BUTYL 2-CARBAMOTHIOYL-2-(3-(5-(4-CYANOPHENOXY)PYRIDIN-2-YL)-2-(2,4- DIFLUOROPHENYL)-3,3-DIFLUORO-2-HYDROXYPROPYL)HYDRAZINE-1-CARBOXYLATE AND PROCESSES OF PREPARATION Dow AgroSciences LLC (US) 2019-10-23 EP claimed
US-20190276403-A1 T-BUTYL 2-CARBAMOTHIOYL-2-(3-(5-(4-CYANOPHENOXY)PYRIDIN-2-YL)-2-(2,4-DIFLUOROPHENYL)-3,3-DIFLUORO-2-HYDROXYPROPYL)HYDRAZINE-1-CARBOXYLATE AND PROCESSES OF PREPARATION DOW AGROSCIENCES LLC (US) 2019-09-12 US claimed
CN-109963837-A 2-aminothioformyl-2- (3- (5- (4-cyanophenoxy) pyridin-2-yl) -2- (2, 4-difluorophenyl) -3, 3-difluoro-2-hydroxypropyl) hydrazine-l-tert-butyl formate and preparation method thereof 美国陶氏益农公司 2019-07-02 CN claimed
EP-0495939-A4 SEQUENTIAL C-TERMINAL DEGRADATION OF PEPTIDES AND PROTEINS 1992-11-25 EP claimed
EP-0495939-A1 SEQUENTIAL C-TERMINAL DEGRADATION OF PEPTIDES AND PROTEINS. HOPE CITY (US) 1992-07-29 EP claimed
EP-0217634-B1 SEQUENCING OF PEPTIDES Beckman Research Institute of the City of Hope (US) 1992-06-10 EP claimed
EP-0483162-A1 SEQUENTIAL C-TERMINAL DEGRADATION OF PEPTIDES AND PROTEINS. HOPE CITY (US) 1992-05-06 EP claimed
WO-1992003737-A1 SEQUENTIAL C-TERMINAL DEGRADATION OF PEPTIDES AND PROTEINS CITY OF HOPE (US) 1992-03-05 WO claimed
WO-1991018008-A1 SEQUENTIAL C-TERMINAL DEGRADATION OF PEPTIDES AND PROTEINS CITY OF HOPE (US) 1991-11-28 WO claimed
US-5059540-A Coupling the peptide with a silane isothiocyanate to form a thiohydantoin derivative CITY OF HOPE (US) 1991-10-22 US claimed
US-5051368-A Method for forming an amino acid thiohydantoin using an N-substituted ketenimine activator APPLIED BIOSYSTEMS, INC. (US) 1991-09-24 US claimed
US-4837165-A COUPLNIG WITH SILYL ISOTHIOCYANATE, CLEAVING, IDENTIFYING AMINO ACID BECKMAN RESEARCH INSTITUTE, CITY OF HOPE (US) 1989-06-06 US claimed
EP-0217634-A2 Sequencing of peptides Beckman Research Institute of the City of Hope (US) 1987-04-08 EP claimed