Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024299 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL4629594 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL28354821 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL7430191 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL19520729 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL28351253 | 0.98 | KCNH2 (0.52) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| Bromide SCHEMBL28351043 | 0.96 | KCNH2 (0.50) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| Bromide SCHEMBL28351331 | 0.96 | KCNH2 (0.50) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| Bromide SCHEMBL28347658 | 0.96 | KCNH2 (0.50) | KCNH2GPR84HIF1AEPAS1ESR1 | |
| SCHEMBL2318840 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2281 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986318-A | Selenocysteine-mediated polypeptide fragment connection method and application thereof in polypeptide/protein synthesis | 华南理工大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117777024-A | Improved process for preparing arylpyrazole nitriles | 江苏优普生物化学科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117024403-A | Phenylpyrazole compound and application thereof | 沈阳化工大学 | 2023-11-10 | — | — | CN | claimed |
| CN-116715719-A | Method for activating polypeptide/protein hydrazide by using 3-methylpyrazole and application of method in polypeptide/protein synthesis | 华南理工大学 | 2023-09-08 | — | — | CN | claimed |
| CN-114213329-B | Preparation method of aryl pyrazole compound | 中国农业科学院兰州畜牧与兽药研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-114181152-B | Preparation method of arylpyrazole drug intermediate | 中国农业科学院兰州畜牧与兽药研究所 | 2023-08-22 | — | — | CN | claimed |
| CN-115850336-A | Aryl-pyrazole axis chiral compound and preparation method and application thereof | 四川大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115677588-A | 2,3,5,5-tetrasubstituted-4-carbonyl imidazole cyclic nitrone compound, preparation method and application | 中国科学院成都有机化学有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115403522-A | Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | claimed |
| EP-0780378-A1 | New 1-aryl pyrazole derivatives and their use as pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1997-06-25 | — | — | EP | claimed |
| WO-1996038044-A1 | A METHOD FOR CONTROLLING FLIES INFESTING MUSHROOMS BY USING A N-ARYLPYRAZOLE OR A N-HETEROARYLPYRAZOLE COMPOUND | RHONE-POULENC AGROCHIMIE (FR) | 1996-12-05 | — | — | WO | claimed |
| EP-0701553-A1 | ARYLPYRAZOLE FUNGICIDES | RHONE POULENC AGROCHIMIE (FR) | 1996-03-20 | — | — | EP | claimed |
| US-5407808-A | Treating tumor with inhibitor of protoporphyrinogen conversion to heme | FMC CORPORATION (US) | 1995-04-18 | — | — | US | claimed |
| EP-0638070-A1 | FUNGICIDAL ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1995-02-15 | — | — | EP | claimed |
| WO-1994029276-A1 | ARYLPYRAZOLE FUNGICIDES | RHONE POULENC AGROCHIMIE (FR) | 1994-12-22 | — | — | WO | claimed |
| US-5298502-A | Exposure to light in presence of oxidase inhibitor | FMC CORPORATION (US) | 1994-03-29 | — | — | US | claimed |
| WO-1993022287-A1 | FUNGICIDAL ARYLPYRAZOLES | RHONE POULENC AGROCHIMIE (FR) | 1993-11-11 | — | — | WO | claimed |
| EP-0447491-B1 | PROTOPORPHYRINOGEN INHIBITORS AND THEIR USE IN COMPOSITIONS FOR DETECTING AND TREATING TUMOURS | FMC CORP (US) | 1993-08-11 | — | — | EP | claimed |
| EP-0222253-A1 | Substituted 5-amino-1-aryl-pyrazoles | BAYER AG (DE) | 1987-05-20 | — | — | EP | claimed |