Zinc Ion

Zinc Ion

SCHEMBL4522012

CCCCCCCCCc1c(S(=O)(=O)[O-])c(S(=O)(=O)[O-])c2ccccc2c1CCCCCCCCC.[Zn+2]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TLR8 Q9NR97 4/20 0.40
KCNH2 Q12809 6/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.37
CTSV O60911 1/20 0.37
CTSL P07711 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9583978 0.97 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL9594056 0.97 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL9583939 0.97 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18141482 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18139712 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18139778 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18139929 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18141290 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18139254 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL18139431 0.91 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163729-A LUBRICATING OIL CHEVRON RESEARCH COMPANY (US) 1979-08-07 US claimed
US-4089790-A Synergistic combinations of hydrated potassium borate, antiwear agents, and organic sulfide antioxidants CHEVRON RESEARCH COMPANY (US) 1978-05-16 US claimed
US-20090192063-A1 Final Drive and Powershift Transmission Lubricants AFTON CHEMICAL CORPORATION (US) 2009-07-30 US disclosed
US-6482778-B2 FOR INCREASING THE STEEL-ON-STEEL COEFFICIENT OF FRICTION IN CONTINUOUSLY VARIABLE TRANSMISSIONS ETHYL CORPORATION 2002-11-19 US disclosed
US-20020032129-A1 ZINC AND PHOSPHORUS CONTAINING TRANSMISSION FLUIDS HAVING ENHANCED PERFORMANCE CAPABILITIES AFTON CHEMICAL INTANGIBLES LLC 2002-03-14 US disclosed
EP-1076087-A1 Zinc and phosphorus containing transmission fluids having enhanced performance capabilities ETHYL CORPORATION (US) 2001-02-14 EP disclosed