SCHEMBL4522758

SCHEMBL4522758

CNC1C=CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14394183 1.00
SCHEMBL12367755 0.83
SCHEMBL13355873 0.78
SCHEMBL16677009 0.74
SCHEMBL18295822 0.74
SCHEMBL14295926 0.73
Hydrochloric Acid SCHEMBL29758795 0.72
SCHEMBL23676820 0.70
SCHEMBL20880021 0.70
SCHEMBL18727731 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591324-A Pyrazinone derivatives, preparation and application thereof 深圳微芯生物科技股份有限公司 2022-06-07 CN disclosed
EP-4006035-A1 QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER Neupharma, Inc. (US) 2022-06-01 EP disclosed
EP-3800678-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2021-04-07 EP disclosed
EP-2508509-A1 PROCESS FOR PREPARATION OF (Z)-CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID COMPOUNDS Sumitomo Chemical Company, Limited (JP) 2012-10-10 EP disclosed
US-20120108614-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES HYDRA BIOSCIENCES, INC. 2012-05-03 US disclosed
WO-2010138820-A2 N,N-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-12-02 WO disclosed
WO-2009061156-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LG CHEM, LTD. (KR) 2009-05-14 WO disclosed
EP-2050769-A2 Olefin polymerization catalyst and process for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2009-04-22 EP disclosed