Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180479 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4534488 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4534884 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4533375 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4528349 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4535194 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4527268 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4528038 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4531101 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 | |
| SCHEMBL4528296 | 1.00 | TYMS (0.61) | TYMSLPAR3LPAR2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |