Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524343 | 0.92 | HPGD (0.49) | MEN1MAPTKMT2ATDP1HPGD | |
| SCHEMBL13256847 | 0.92 | HPGD (0.49) | MEN1MAPTKMT2ATDP1HPGD | |
| SCHEMBL4524340 | 0.92 | HPGD (0.49) | MEN1MAPTKMT2ATDP1HPGD | |
| SCHEMBL7836427 | 0.90 | MEN1 (0.49) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL7838259 | 0.88 | MEN1 (0.47) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL7828865 | 0.87 | MEN1 (0.47) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL7836724 | 0.87 | MEN1 (0.47) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL7829767 | 0.87 | MEN1 (0.46) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL3284122 | 0.86 | MAPT (0.59) | MEN1MAPTKMT2ATDP1CSNK2A2 | |
| SCHEMBL7837617 | 0.85 | MEN1 (0.46) | MEN1MAPTKMT2ATDP1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566787-B2 | Small molecule cyclin D1 ablative agents | THE OHIO STATE UNIVERSITY (US) | 2009-07-28 | — | — | US | disclosed |
| US-20060252802-A1 | Small molecule cyclin D1 ablative agents | NIH - DEITR | 2006-11-09 | — | — | US | disclosed |
| WO-2006069217-A2 | SMALL MOLECULE CYCLIN D1 ABLATIVE AGENTS | THE OHIO STATE RESEARCH FOUNDATION (US) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252802-A1 | Small molecule cyclin D1 ablative agents | CDK4, CCNK, CCNA1 | MEN1 3068/4885MAPT 4563/4885KMT2A 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.