Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880616 | 0.91 | S1PR1 (0.62) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL4522352 | 0.91 | S1PR1 (0.53) | S1PR1CNR2TP53MAPTALDH1A1 | |
| SCHEMBL4522168 | 0.86 | CNR2 (0.47) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL3881597 | 0.85 | S1PR1 (0.54) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL4522443 | 0.85 | S1PR1 (0.53) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL4509065 | 0.83 | S1PR1 (0.68) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL4522766 | 0.83 | S1PR1 (0.61) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL3881577 | 0.82 | S1PR1 (0.60) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL3880113 | 0.81 | S1PR1 (0.62) | S1PR1CNR2TP53MAPTMAOB | |
| SCHEMBL3888378 | 0.80 | S1PR1 (0.53) | S1PR1CNR2MAPTALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | NOVARTIS AG (CH) | 2009-12-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | CYP1A2, CYP4B1, CYP1B1 | S1PR1 3084/4885CNR2 538/4885KCNK3 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.