SCHEMBL4527034

SCHEMBL4527034

OC[C@H]1O[C@@H](O)[C@H](Oc2ccc3ccc4cccc5ccc2c3c45)[C@@H](O)[C@H]1O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CD209 Q9NNX6 1/20 0.38
SLC5A2 P31639 4/20 0.38
SLC5A1 P13866 3/20 0.38
SLC28A3 Q9HAS3 2/20 0.37
ATM Q13315 1/20 0.37
PYGL P06737 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
EPHX2 P34913 1/20 0.36
LGALS9 O00182 2/20 0.35
LGALS1 P09382 2/20 0.35
LGALS3 P17931 2/20 0.35
LGALS7; LGALS7B P47929 2/20 0.35
LGALS8 O00214 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512267 0.87 SLC5A2 (0.32) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL9185613 0.86 SLC28A3 (0.50) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL15202628 0.85 ATM (0.52) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL13868797 0.85 ATM (0.52) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL4513194 0.85 ATM (0.52) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL4511980 0.85 ATM (0.52) CD209SLC5A2SLC5A1SLC28A3ATM
SCHEMBL9013945 0.83 CD209 (0.54) CD209SLC5A2SLC28A3ATMPYGL
SCHEMBL11121957 0.83 CD209 (0.54) CD209SLC5A2SLC28A3ATMPYGL
SCHEMBL22125691 0.83 CD209 (0.54) CD209SLC5A2SLC28A3ATMPYGL
SCHEMBL7747632 0.83 CD209 (0.54) CD209SLC5A2SLC28A3ATMPYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140295403-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-10-02 US disclosed
US-8632966-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-01-21 US disclosed
US-20130217041-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-08-22 US disclosed
US-8377686-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-02-19 US disclosed
US-20090117600-A1 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-05-07 US disclosed
US-7402426-B2 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-07-22 US disclosed
EP-1539986-B1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS UNIV KINGSTON (CA) 2007-07-18 EP disclosed
US-20040106164-A1 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-06-03 US disclosed