Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4531881 | 0.90 | ABCG2 (0.55) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| Trifluoroacetic Acid SCHEMBL4529644 | 0.88 | CYP1A2 (0.52) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL13963127 | 0.88 | CYP1A2 (0.66) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL13963121 | 0.82 | CYP1A2 (0.77) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL4531885 | 0.82 | CYP1A2 (0.49) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL20355745 | 0.80 | CYP1A2 (0.73) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL13963133 | 0.80 | CYP1A2 (0.58) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL13963137 | 0.80 | CYP1A2 (0.64) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| Hydrochloric Acid SCHEMBL4533038 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A | |
| SCHEMBL13963126 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP2D6DNMT1DNMT3LDNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018150-A1 | 5-Ht2b Receptor Antagonists | ASTERAND UK LIMITED (GB) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018150-A1 | 5-Ht2b Receptor Antagonists | HTR2B, HTR1B, HTR3B | CYP1A2 482/4885CYP2D6 520/4885DNMT1 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.