Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225932 | 0.93 | TDP1 (0.63) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL31226174 | 0.93 | TDP1 (0.63) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL31251932 | 0.90 | TDP1 (0.81) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL18484173 | 0.90 | TSHR (0.53) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL7199968 | 0.90 | TDP1 (0.76) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL25835454 | 0.89 | TDP1 (0.61) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL17162055 | 0.89 | TDP1 (0.78) | TDP1GAACA1CA2CA12 | |
| SCHEMBL4415666 | 0.89 | TDP1 (0.73) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL29091668 | 0.89 | TDP1 (0.73) | TDP1GAACYP3A4CA1CA2 | |
| SCHEMBL31225835 | 0.88 | TDP1 (0.68) | TDP1GAACYP3A4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507764-B2 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | TEGO BIOSCIENCES CORPORATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-20050143327-A1 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | LUNA LABS USA, LLC | 2005-06-30 | — | — | US | disclosed |
| WO-2005037711-A1 | AMPHIPHILIC [5:1]- AND [3:3]- HEXAKISADDUCTS OF FULLERENES | C SIXTY INC. (US) | 2005-04-28 | — | — | WO | disclosed |