SCHEMBL45279

SCHEMBL45279

C=C[CH]N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3774472 1.00
SCHEMBL26677755 0.96
SCHEMBL2054206 0.69
SCHEMBL27992237 0.67 TSHR (0.39)
Butadiene SCHEMBL27861655 0.67
SCHEMBL152040 0.67
SCHEMBL449642 0.65
Dimethylformamide SCHEMBL28376908 0.64
Hydrochloric Acid SCHEMBL3468882 0.64
Hydrochloric Acid SCHEMBL1308448 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240140958-A1 FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF TABOMEDEX BIOSCIENCES INC (US) 2024-05-02 US claimed
WO-2024073709-A2 MODIFIED OLIGONUCLEOTIDES AND DOUBLE-STRANDED RNAS ALNYLAM PHARMACEUTICALS, INC. (US) 2024-04-04 WO claimed
CN-117285484-A Benzothiadiazine 1, 1-dioxide compounds inhibiting HDAC6 enzyme, preparation method and application thereof 上海医药工业研究院有限公司 2023-12-26 CN claimed
CN-117247358-A Benzodiazepine compound with HDAC6 inhibition activity and preparation method and application thereof 上海医药工业研究院有限公司 2023-12-19 CN claimed
CN-117247336-A Hydroxamic acid compound capable of inhibiting HDAC6 as well as preparation method and application thereof 上海医药工业研究院有限公司 2023-12-19 CN claimed
CN-117229229-A Benzothiadiazine compound for inhibiting HDAC6, and preparation method and application thereof 上海医药工业研究院有限公司 2023-12-15 CN claimed
US-20230399304-A1 COVALENT INHIBITORS OF CREATINE KINASE (CK) AND USES THEREOF FOR TREATING AND PREVENTING CANCER DANA-FARBER CANCER INSTITUTE, INC. 2023-12-14 US claimed
EP-4274833-A1 FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF Tabomedex Biosciences, Inc. (US) 2023-11-15 EP claimed
EP-4232161-A1 COVALENT INHIBITORS OF CREATINE KINASE (CK) AND USES THEREOF FOR TREATING AND PREVENTING CANCER Dana-Farber Cancer Institute, Inc. (US) 2023-08-30 EP claimed
CN-116323571-A Covalent inhibitors of Creatine Kinase (CK) and their use for the treatment and prevention of cancer 丹娜法伯癌症研究院 2023-06-23 CN claimed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP claimed
EP-0019161-B1 IMPREGNATING AND BINDING AGENT BASED ON AQUEOUS DISPERSIONS OF COPOLYMERS HAVING EPOXY GROUPS, AND THEIR USE BASF Aktiengesellschaft (DE) 1983-04-13 EP claimed
EP-0073143-A2 Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides Ryan, James Walter (US) 1983-03-02 EP claimed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 EP claimed
EP-0030526-A1 New phenyl-azacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds Astra Läkemedel Aktiebolag (SE) 1981-06-17 EP claimed
WO-1981001552-A1 NEW PHENYL-AZACYCLOALKANES ASTRA LAEKEMEDEL AB (SE) 1981-06-11 WO claimed
US-4250240-A Photosensitive material for use in electrophotography RICOH COMPANY, LTD. (JP) 1981-02-10 US claimed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP claimed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US claimed
US-3953596-A 8-Oxa-3-azabicyclo(3.2.1)octane analgesic compositions and method of alleviating pain in animals ICI UNITED STATES INC. (US) 1976-04-27 US claimed