Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528314 | 1.00 | CYSLTR2 (0.48) | CYSLTR2TAS1R3TAS1R1HRH3SLC8A1 | |
| SCHEMBL4525421 | 0.92 | CYSLTR2 (0.57) | CYSLTR2TAS1R3TAS1R1SLC8A1F9 | |
| SCHEMBL4525419 | 0.92 | CYSLTR2 (0.57) | CYSLTR2TAS1R3TAS1R1SLC8A1F9 | |
| SCHEMBL4523082 | 0.86 | CYSLTR2 (0.64) | CYSLTR2AXLMERTKKMT2A | |
| SCHEMBL4523085 | 0.86 | CYSLTR2 (0.64) | CYSLTR2AXLMERTKKMT2A | |
| SCHEMBL4521068 | 0.85 | CYSLTR2 (0.52) | CYSLTR2APAF1MAPTKMT2APRSS1 | |
| SCHEMBL4521070 | 0.85 | CYSLTR2 (0.52) | CYSLTR2APAF1MAPTKMT2APRSS1 | |
| SCHEMBL4527322 | 0.84 | CYSLTR2 (0.56) | CYSLTR2APAF1MAPTKMT2APRSS1 | |
| SCHEMBL13918505 | 0.84 | CYSLTR2 (0.52) | CYSLTR2MAPTKMT2APRSS1PRSS2 | |
| SCHEMBL4508320 | 0.84 | CYSLTR2 (0.56) | CYSLTR2APAF1MAPTKMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | CYSLTR2 1426/4885TAS1R3 4714/4885TAS1R1 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.