Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532450 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4530283 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4531940 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4534916 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4529308 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4530049 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4525595 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4533367 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4055586 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL1940600 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123516-A1 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-05-14 | — | — | US | disclosed |