Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.42 |
| ▸ | CDK8 | P49336 | 5/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | UGCG | Q16739 | 3/20 | 0.40 |
| ▸ | RBP4 | P02753 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL1572911 | 0.96 | CCNC (0.39) | CCNCCDK8CHRNA7DYRK1AUGCG | |
| SCHEMBL4232915 | 0.87 | GSK3B (0.46) | CCNCCDK8CHRNA7UGCGRBP4 | |
| SCHEMBL1573103 | 0.86 | CCNC (0.42) | CCNCCDK8DYRK1ARBP4JAK2 | |
| SCHEMBL1572778 | 0.85 | CHRNA7 (0.52) | CHRNA7RBP4HTR3AMAPT | |
| SCHEMBL1573183 | 0.84 | GSK3B (0.53) | DYRK1AUGCGRBP4 | |
| Hydrochloric Acid SCHEMBL4223898 | 0.84 | CHRNA7 (0.51) | CHRNA7RBP4HTR3AMAPT | |
| SCHEMBL1572980 | 0.83 | MAPT (0.43) | CCNCCDK8CHRNA7UGCGMAPT | |
| SCHEMBL1572934 | 0.82 | DYRK1A (0.47) | CHRNA7DYRK1ARBP4 | |
| SCHEMBL1572635 | 0.82 | LRRK2 (0.44) | CHRNA7DYRK1AUGCGRBP4 | |
| SCHEMBL1635357 | 0.82 | AHR (0.43) | CHRNA7DYRK1AUGCGRBP4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325939-A1 | 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF | XIE WENGE | 2009-12-31 | — | — | US | disclosed |
| US-20090325939-A1 | 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF | XIE WENGE | 2009-12-31 | — | — | US | disclosed |
| US-7632831-B2 | 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632831-B2 | 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325939-A1 | 1H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA1, CHRNA5 | CCNC 3969/4885CDK8 1105/4885CHRNA7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.