SCHEMBL4530048

SCHEMBL4530048

C[Si](C)(Cl)CCCCCCCl

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4525122 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4528652 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL8756007 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL5575657 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4526688 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4530934 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4535326 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4529846 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4534717 1.00 TSHR (0.43) TSHRALDH1A1TDP1
SCHEMBL4534042 1.00 TSHR (0.43) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722334-B Preparation method of flame-retardant pentane foaming agent 宁波中金石化有限公司 2020-05-29 CN claimed
CN-114761612-A In-situ PECVD capping layer 朗姆研究公司 2022-07-15 CN disclosed
CN-107722334-B Preparation method of flame-retardant pentane foaming agent 宁波中金石化有限公司 2020-05-29 CN disclosed
US-20090123516-A1 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS-THERAPEUTIC SAMS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2009-05-14 US disclosed
WO-2007019478-A2 DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2007-02-15 WO disclosed
EP-0484857-B1 Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent SAGAMI CHEM RES (JP) 1997-05-07 EP disclosed
US-5624680-A SKIN ABSORPTION OF DRUGS WITH POLYETHERSILOXANE BLOCK COPOLYMERS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-04-29 US disclosed
EP-0710688-A1 HYDROXYSILYL-TERMINATED POLYOXYETHYLENE COMPOUND, QUATERNARY-SALT-TERMINATED BLOCK COPOLYMER, AND PERCUTANEOUS ABSORPTION PROMOTER SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-05-08 EP disclosed
US-5200488-A POLYORGANOSILOXANE HAVING A QUATERNARY SALT AT ITS ONE TERMINAL AND PERCUTANEOUS ABSORPTION-PROMOTING AGENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-04-06 US disclosed