SCHEMBL4530171

SCHEMBL4530171

CCCCCCCCCCCCNCCC[SiH](O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
ALDH1A1 P00352 1/20 0.59
S1PR2 O95136 5/20 0.48
S1PR4 O95977 5/20 0.48
S1PR1 P21453 5/20 0.48
S1PR3 Q99500 5/20 0.48
S1PR5 Q9H228 1/20 0.48
EPHX1 P07099 7/20 0.45
ADH1B P00325 2/20 0.43
ADH1C P00326 2/20 0.43
ADH1A P07327 2/20 0.43
ADH7 P40394 2/20 0.43
ANPEP P15144 1/20 0.43
ERAP2 Q6P179 1/20 0.43
ADH4 P08319 1/20 0.43
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
GNAI3 P08754 1/20 0.39
GNAO1 P09471 1/20 0.39
GNAI1 P63096 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15004569 1.00 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4521500 0.95 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4530758 0.93 TSHR (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4533578 0.91 TSHR (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4525570 0.83 TSHR (0.52) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL25210211 0.83 TSHR (0.87) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL6545006 0.83 TSHR (0.87) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL5165020 0.83 TSHR (0.87) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL21611676 0.83 TSHR (0.87) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL8980623 0.83 TSHR (0.87) TSHRALDH1A1S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed