Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4530640 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AHDAC1HDAC2HDAC3 | |
| SCHEMBL4530636 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AHDAC1HDAC2HDAC3 | |
| SCHEMBL4509890 | 0.88 | PPARA (0.65) | SMN1; SMN2RAB9AHDAC1HDAC2HDAC3 | |
| SCHEMBL4509884 | 0.88 | PPARA (0.65) | SMN1; SMN2RAB9AHDAC1HDAC2HDAC3 | |
| SCHEMBL5208826 | 0.85 | CA12 (0.56) | SMN1; SMN2RAB9APPARANPC1MAPT | |
| SCHEMBL5640723 | 0.84 | HDAC1 (0.58) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL5640719 | 0.84 | HDAC1 (0.58) | SMN1; SMN2HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL4518363 | 0.84 | PPARA (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4518366 | 0.84 | PPARA (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL4508132 | 0.83 | PPARA (0.48) | SMN1; SMN2RAB9AHDAC1HDAC2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | SMN1; SMN2 3233/4885RAB9A 3779/4885HDAC1 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.