⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485848 | 0.74 | — | — | |
| SCHEMBL3496894 | 0.74 | — | — | |
| SCHEMBL10658392 | 0.74 | — | — | |
| SCHEMBL544154 | 0.72 | — | — | |
| Water SCHEMBL27647043 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL10476096 | 0.72 | — | — | |
| SCHEMBL4539625 | 0.70 | MIF (0.39) | — | |
| SCHEMBL4875537 | 0.69 | — | — | |
| Benzene SCHEMBL7919589 | 0.68 | MIF (0.43) | — | |
| Formic Acid SCHEMBL27446827 | 0.67 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314121-B2 | Imidazolone derivatives, preparation thereof as drugs, pharmaceutical compositions, and use thereof as protein kinase inhibitors, in particular CDC7 | SANOFI (FR) | 2012-11-20 | — | — | US | disclosed |
| US-20090253679-A1 | NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7 | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | US | disclosed |