SCHEMBL4532065

SCHEMBL4532065

OCCOCCOCCOCCCCCCCCCCCSSc1ccccn1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 15/20 0.42
HDAC2 Q92769 13/20 0.42
EHMT2 Q96KQ7 1/20 0.42
EHMT1 Q9H9B1 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
HDAC4 P56524 2/20 0.36
HDAC6 Q9UBN7 1/20 0.36
GRM2 Q14416 1/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10326955 0.92 EHMT2 (0.44) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL10326956 0.92 EHMT2 (0.50) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL11827062 0.90 EHMT2 (0.52) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL18369713 0.89 EHMT2 (0.47) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL15140934 0.89 EHMT2 (0.47) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL31290207 0.89 EHMT2 (0.47) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL29796129 0.89 EHMT2 (0.47) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL30833293 0.87 EHMT2 (0.48) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL14984823 0.87 EHMT2 (0.48) HDAC1HDAC2EHMT2EHMT1APOBEC3G
SCHEMBL9889211 0.86 EHMT2 (0.42) HDAC1HDAC2EHMT2EHMT1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers SURFACE LOGIX, INC. 2009-12-31 US disclosed
US-7439056-B2 Peelable and resealable devices for arraying materials SURFACE LOGIX INC. (US) 2008-10-21 US disclosed
US-7371563-B2 Peelable and resealable devices for biochemical assays SURFACE LOGIX, INC. (US) 2008-05-13 US disclosed
US-7351575-B2 Methods for processing biological materials using peelable and resealable devices SURFACE LOGIX, INC. (US) 2008-04-01 US disclosed
US-7001740-B2 Methods of arraying biological materials using peelable and resealable devices SURFACE LOGIX, INC. (US) 2006-02-21 US disclosed
US-6967074-B2 Methods of detecting immobilized biomolecules SURFACE LOGIX, INC. (US) 2005-11-22 US disclosed
US-20050250097-A1 METHODS OF ARRAYING BIOLOGICAL MATERIALS USING PEELABLE AND RESEALABLE DEVICES SURFACE LOGIX, LLC 2005-11-10 US disclosed
US-20050100974-A1 METHODS OF DETECTING IMMOBILIZED BIOMOLECULES SURFACE LOGIX, LLC 2005-05-12 US disclosed
US-6803205-B2 MONITORING ENZYME ACTIVITY IN SAMPLE; OBTAIN ENZYME SAMPLE, INSERT INTO RESEALABLE APPARATUS, EXPOSE TO SUBSTRATE, MEASURE ENZYME ACTIVITY SURFACE LOGIX, INC. 2004-10-12 US disclosed
US-6764768-B2 SELF ASSEMBLING MONOLAYERS OF ALKANETHIOLATES ARCH DEVELOPMENT CORPORATION 2004-07-20 US disclosed
US-20030073228-A1 Peelable and resealable devices for arraying materials SURFACE LOGIX, LLC 2003-04-17 US disclosed
US-20030068637-A1 Methods for processing biological materials using peelable and resealable devices SURFACE LOGIX, LLC 2003-04-10 US disclosed
WO-2003012392-A2 RESEALABLE AND SEALABLE DEVICES FOR BIOCHEMICAL ASSAYS SURFACE LOGIX, INC. (US) 2003-02-13 WO disclosed
US-20030032046-A1 Peelable and resealable devices for biochemical assays SURFACE LOGIX, LLC 2003-02-13 US disclosed
US-20030032076-A1 Methods of measuring enzyme activity using peelable and resealable devices SURFACE LOGIX, LLC 2003-02-13 US disclosed
US-20020119305-A1 Controlled release composition ARCH DEVELOPMENT CORPORATION 2002-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325262-A1 Immobilization of biological molecules onto surfaces coated with monolayers EPCAM, ICAM1, MB HDAC1 1124/4885HDAC2 1167/4885EHMT2 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.