Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 11/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9936887 | 0.82 | NR4A2 (0.48) | NR4A2CREBBPAXLMAP2K1GAA | |
| SCHEMBL9937058 | 0.77 | NR4A2 (1.00) | NR4A2CREBBPMAP2K1LMNARAB9A | |
| SCHEMBL1607800 | 0.71 | NR4A2 (0.62) | NR4A2CREBBPAXLMAP2K1GAA | |
| SCHEMBL31753965 | 0.71 | NR4A2 (0.62) | NR4A2CREBBPAXLMAP2K1GAA | |
| SCHEMBL25088402 | 0.71 | NR4A2 (0.49) | NR4A2CREBBPAXLMAP2K1 | |
| SCHEMBL14893447 | 0.70 | ATM (0.49) | NR4A2GAATSHRPDE4DALDH1A1 | |
| SCHEMBL6871302 | 0.70 | NR4A2 (0.63) | NR4A2CREBBPMAP2K1ALDH1A1MEN1 | |
| SCHEMBL9937275 | 0.70 | NR4A2 (0.58) | NR4A2CREBBPAXLMAP2K1 | |
| SCHEMBL17818802 | 0.70 | NR4A2 (0.58) | NR4A2CREBBPAXLMAP2K1 | |
| SCHEMBL24704112 | 0.70 | MAP2K1 (0.42) | NR4A2CREBBPAXLMAP2K1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |