Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534447 | 0.95 | PDE4B (0.58) | PDE4BPDE4D | |
| SCHEMBL4508961 | 0.89 | PDE4B (0.55) | PDE4B | |
| Trifluoroacetic Acid SCHEMBL4520838 | 0.88 | PDE4B (0.51) | PDE4B | |
| SCHEMBL4532337 | 0.85 | PDE4B (0.45) | PDE4B | |
| SCHEMBL1434910 | 0.85 | PDE4B (0.61) | PDE4BPDE4D | |
| SCHEMBL4508317 | 0.84 | PDE4B (0.62) | PDE4BPDE4D | |
| Trifluoroacetic Acid SCHEMBL4517598 | 0.84 | PDE4B (0.48) | PDE4B | |
| SCHEMBL1434714 | 0.84 | PDE4B (0.62) | PDE4BPDE4D | |
| SCHEMBL1434884 | 0.83 | PDE4B (0.63) | PDE4BPDE4D | |
| SCHEMBL1561194 | 0.83 | PDE4B (0.61) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090326003-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326003-A1 | PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PDE4 INHIBITORS | PDE4A, PDE4B, PDE12 | PDE4B 2/4885PDE4D 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.