Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655700 | 1.00 | ATM (0.38) | ATMHRH3 | |
| SCHEMBL18173552 | 0.89 | ATM (0.36) | ATM | |
| SCHEMBL14941417 | 0.89 | ATM (0.36) | ATM | |
| SCHEMBL1440281 | 0.89 | HRH3 (0.35) | ATMHRH3 | |
| SCHEMBL320728 | 0.84 | ATM (0.47) | ATM | |
| SCHEMBL30181786 | 0.82 | HRH3 (0.34) | HRH3 | |
| SCHEMBL4445004 | 0.76 | — | — | |
| SCHEMBL2025950 | 0.76 | — | — | |
| SCHEMBL5743233 | 0.75 | CHRM3 (0.40) | — | |
| SCHEMBL1108992 | 0.75 | CHRM4 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014078331-A1 | N-(ARYLALKYL)-N'-PYRAZOLYL-UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| EP-2638031-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062783-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-05-18 | — | — | WO | disclosed |