Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837258 | 0.84 | EGFR (1.00) | EGFR | |
| SCHEMBL6836432 | 0.84 | EGFR (1.00) | EGFR | |
| SCHEMBL6837209 | 0.82 | EGFR (1.00) | EGFR | |
| SCHEMBL6836410 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL6837285 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL14310712 | 0.81 | EGFR (0.78) | EGFR | |
| SCHEMBL6837694 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL2986222 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL6833307 | 0.81 | EGFR (1.00) | EGFR | |
| SCHEMBL5565343 | 0.81 | EGFR (0.68) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070328-A1 | MODULATORS OF THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) PATHWAY FOR USE IN THE TREATMENT OR PREVENTION OF SUBSTANCE ABUSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-06-04 | — | — | WO | disclosed |