Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.52 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.52 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.52 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.52 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.52 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.52 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.52 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.52 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531446 | 0.86 | PPARG (0.45) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4534308 | 0.86 | PPARG (0.50) | KMT2AMEN1TDP1SLC6A9CHRM1 | |
| SCHEMBL13757732 | 0.85 | MAPT (0.51) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2844450 | 0.85 | HDAC7 (0.55) | KMT2ACHRM1HDAC1HDAC3HDAC4 | |
| SCHEMBL13757731 | 0.84 | KMT2A (0.50) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4538126 | 0.84 | KLK7 (0.53) | KMT2AMEN1MAPTHDAC1HDAC3 | |
| SCHEMBL4536194 | 0.82 | HDAC1 (0.46) | KMT2AMEN1CHRM1HDAC1HDAC3 | |
| SCHEMBL2844443 | 0.82 | CYP1A2 (0.50) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL4541582 | 0.81 | HDAC4 (0.49) | KMT2AMEN1MAPTHDAC1HDAC3 | |
| SCHEMBL4534419 | 0.81 | HDAC4 (0.49) | KMT2AMEN1HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| WO-2008122115-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | GCGR 2053/4885ADCY6 2321/4885ADCY3 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.