Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.89 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512506 | 0.94 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1NR1H4ALDH1A1MEN1 | |
| SCHEMBL29438768 | 0.94 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1NR1H4ALDH1A1MEN1 | |
| SCHEMBL13932996 | 0.93 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1NR1H4ALDH1A1MEN1 | |
| SCHEMBL4527529 | 0.92 | CYSLTR2 (0.95) | CYSLTR2NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL13918311 | 0.90 | CYSLTR2 (0.89) | CYSLTR2NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL4527148 | 0.90 | CYSLTR2 (0.88) | CYSLTR2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13918385 | 0.89 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1NR1H4ALDH1A1MEN1 | |
| SCHEMBL13918344 | 0.89 | CYSLTR2 (0.90) | CYSLTR2CYSLTR1NR1H4ALDH1A1MEN1 | |
| SCHEMBL4527632 | 0.88 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13918332 | 0.88 | CYSLTR2 (0.88) | CYSLTR2NR1H4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | disclosed |
| US-20060154912-A1 | Isophtalic acid derivatives | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154912-A1 | Isophtalic acid derivatives | VHL, FABP3, CPT1A | CYSLTR2 1426/4885CYSLTR1 1675/4885NR1H4 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.