Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13045596 | 0.95 | TSHR (0.42) | HIF1ATSHRTRPA1FAAHTRPV1 | |
| SCHEMBL12675322 | 0.90 | — | — | |
| SCHEMBL15038 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL43799 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL4251350 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL8742957 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL10809632 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL1477623 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL3238884 | 0.82 | MIF (0.38) | TRPA1 | |
| SCHEMBL2231808 | 0.82 | MIF (0.38) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457593-A1 | Cyclic RGD peptides of amino acids based on thiazoles or oxazoles as selective antagonists of the alpha-v beta-3 integrin | Lykera Biomed S.A. (ES) | 2012-05-30 | — | — | EP | disclosed |
| WO-2012062777-A1 | CYCLIC RGD PEPTIDES OF AMINO ACIDS BASED ON THIAZOLES OR OXAZOLES AS SELECTIVE ANTAGONISTS OF THE ALFA ανβ3 INTEGRIN | LYKERA BIOMED SA (ES) | 2012-05-18 | — | — | WO | disclosed |