Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | MPL | P40238 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475436 | 0.84 | MAPT (0.58) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL27469571 | 0.84 | MAPT (0.58) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL8389286 | 0.83 | MAPT (0.48) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL30475440 | 0.83 | ERAP1 (0.59) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL30443913 | 0.83 | GRIN2D (0.59) | MAPTKDM4EALDH1A1GAACASP1 | |
| SCHEMBL5684603 | 0.83 | GRIN2D (0.59) | MAPTKDM4EALDH1A1GAACASP1 | |
| Methane SCHEMBL3681080 | 0.82 | MAPT (0.46) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL8389062 | 0.78 | MPL (0.56) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL11537832 | 0.77 | MPL (0.51) | MAPTMAPK1NPSR1KDM4EALDH1A1 | |
| SCHEMBL9141120 | 0.76 | KDM4E (0.55) | MAPTKDM4EALDH1A1GAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103705496-B | Positively charged water-soluble prodrugs of aryl and heteroaryl propionic acids with fast skin penetration rate | 于崇曦 | 2017-03-01 | — | — | CN | claimed |
| CN-103705496-B | Positively charged water-soluble prodrugs of aryl and heteroaryl propionic acids with fast skin penetration rate | 于崇曦 | 2017-03-01 | — | — | CN | disclosed |
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |